Overview | Target-Function-Expression | miRNA expression | miRNA with inferred function | Documentation
1. Organism
Human [hg17] Mouse [mm7]
2. Target Prediction Methods
Algorithm : miRanda PicTar-4Way PicTar-5Way TargetScanS
MiRanda 4.0,conserved in at least two species PicTar4Way, 4 Species Conservation Human/Mouse/Rat/Dog PicTar5Way, 5 Species Conservation Human/Mouse/Rat/Dog/Chicken TargetScanS, 5 Species Conservation Human/Mouse/Rat/Dog/Chicken
3. Search miRNAs by
Gene Ontology
(Query examples : GO:0003713, GO:0005488, GO:0005581)
Pathway
Hs_Acetylation and Deacetylation of RelA in The Nucleus Hs_Acetylcholine_Synthesis Hs_Actions of Nitric Oxide in the Heart Hs_Activation of cAMP-dependent protein kinase, PKA Hs_Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor Hs_Activation of PKC through G protein coupled receptor Hs_Activation of Src by Protein-tyrosine phosphatase alpha Hs_Acute Myocardial Infarction Hs_Adhesion and Diapedesis of Granulocytes Hs_Adhesion and Diapedesis of Lymphocytes Hs_Adhesion Molecules on Lymphocyte Hs_ADP-Ribosylation Factor Hs_Agrin in Postsynaptic Differentiation Hs_Ahr Signal Transduction Pathway Hs_AKAP95 role in mitosis and chromosome dynamics Hs_AKT Signaling Pathway Hs_Alanine_and_aspartate_metabolism Hs_ALK in cardiac myocytes Hs_Alkaloid_biosynthesis_I Hs_Alpha-synuclein and Parkin-mediated proteolysis in Parkinsons disease Hs_Aminoacyl-tRNA_biosynthesis Hs_Aminophosphonate_metabolism Hs_Aminosugars_metabolism Hs_Androgen_and_estrogen_metabolism Hs_Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling Hs_Angiotensin-converting enzyme 2 regulates heart function Hs_Anthrax Toxin Mechanism of Action Hs_Antigen Dependent B Cell Activation Hs_Antigen Processing and Presentation Hs_Antisense Pathway Hs_Apoptosis Hs_Apoptotic DNA fragmentation and tissue homeostasis Hs_Apoptotic Signaling in Response to DNA Damage Hs_Arginine_and_proline_metabolism Hs_Ascorbate_and_aldarate_metabolism Hs_Aspirin Blocks Signaling Pathway Involved in Platelet Activation Hs_ATM Signaling Pathway Hs_Attenuation of GPCR Signaling Hs_B Cell Receptor Complex Hs_B Cell Survival Pathway Hs_Basic Mechanisms of SUMOylation Hs_BCR Signaling Pathway Hs_beta-Alanine_metabolism Hs_beta-arrestins in GPCR Desensitization Hs_Bile_acid_biosynthesis Hs_Bioactive Peptide Induced Signaling Pathway Hs_Biosynthesis of Arginine in Bacteria Hs_Biosynthesis of neurotransmitters Hs_Biosynthesis of Proline in Bacteria Hs_Biotin_metabolism Hs_Blockade of Neurotransmitter Relase by Botulinum Toxin Hs_Blood_Clotting_Cascade Hs_Bone Remodelling Hs_BRCA1-dependent Ub-ligase activity Hs_BTG family proteins and cell cycle regulation Hs_Butanoate_metabolism Hs_Bystander B Cell Activation Hs_C21-Steroid_hormone_metabolism Hs_Ca++/ Calmodulin-dependent Protein Kinase Activation Hs_Cadmium induces DNA synthesis and proliferation in macrophages Hs_Calcium Signaling by HBx of Hepatitis B virus Hs_Calcium_Channels Hs_Carbon_fixation Hs_Cardiac Protection Against ROS Hs_CARM1 and Regulation of the Estrogen Receptor Hs_Caspase Cascade in Apoptosis Hs_Catabolic pathway for asparagine and asparate Hs_CBL mediated ligand-induced downregulation of EGF receptors Hs_CCR3 signaling in Eosinophils Hs_CD40L Signaling Pathway Hs_cdc25 and chk1 Regulatory Pathway in response to DNA damage Hs_CDK Regulation of DNA Replication Hs_Cell Cycle: G1/S Check Point Hs_Cell Cycle: G2/M Checkpoint Hs_Cell to Cell Adhesion Signaling Hs_Cells and Molecules involved in local acute inflammatory response Hs_Cell_Cycle Hs_Ceramide Signaling Pathway Hs_Chaperones modulate interferon Signaling Pathway Hs_Cholesterol_Biosynthesis Hs_ChREBP regulation by carbohydrates and cAMP Hs_Chromatin Remodeling byHsWI/SNF ATP-dependent Complexes Hs_Circadian Rhythms Hs_Citrate_cycle_(TCA_cycle) Hs_Complement Pathway Hs_Complement_Activation_Classical Hs_Control of Gene Expression by Vitamin D Receptor Hs_Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK) Hs_Corticosteroids and cardioprotection Hs_CTCF: First Multivalent Nuclear Factor Hs_CTL mediated immune response against target cells Hs_CXCR4 Signaling Pathway Hs_Cyanoamino_acid_metabolism Hs_Cyclin E Destruction Pathway Hs_Cycling of Ran in nucleocytoplasmic transport Hs_Cyclins and Cell Cycle Regulation Hs_Cysteine_metabolism Hs_Cystic fibrosis transmembrane conductance regulator and beta 2 adrenergic receptor pathway Hs_Cytokine Network Hs_Cytokines and Inflammatory Response Hs_D-Arginine_and_D-ornithine_metabolism Hs_D-Glutamine_and_D-glutamate_metabolism Hs_D4-GDI Signaling Pathway Hs_Degradation of the RAR and RXR by the proteasome Hs_Dendritic cells in regulating TH1 and TH2 Development Hs_Deregulation of CDK5 in Alzheimers Disease Hs_Dicer Pathway Hs_Double Stranded RNA Induced Gene Expression Hs_Downregulated of MTA-3 in ER-negative Breast Tumors Hs_E2F1 Destruction Pathway Hs_Effects of calcineurin in Keratinocyte Differentiation Hs_EGF Signaling Pathway Hs_Eicosanoid Metabolism Hs_Eicosanoid_Synthesis Hs_Electron Transport Reaction in Mitochondria Hs_Electron_Transport_Chain Hs_Eph Kinases and ephrins support platelet aggregation Hs_EPO Signaling Pathway Hs_ER-associated degradation (ERAD) Pathway Hs_Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia Hs_Erk1/Erk2 Mapk Signaling pathway Hs_Erythrocyte Differentiation Pathway Hs_Erythropoietin mediated neuroprotection through NF-kB Hs_Estrogen-responsive protein Efp controls cell cycle and breast tumors growth Hs_Eukaryotic protein translation Hs_Extrinsic Prothrombin Activation Pathway Hs_FAS signaling pathway ( CD95 ) Hs_Fatty_acid_biosynthesis_(path_1) Hs_Fatty_acid_biosynthesis_(path_2) Hs_Fatty_Acid_Degradation Hs_Fatty_acid_metabolism Hs_Fatty_Acid_Synthesis Hs_Fc Epsilon Receptor I Signaling in Mast Cells Hs_Feeder Pathways for Glycolysis Hs_Fibrinolysis Pathway Hs_fMLP induced chemokine gene expression in HMC-1 cells Hs_Folate_biosynthesis Hs_FOSB gene expression and drug abuse Hs_Free Radical Induced Apoptosis Hs_Fructose_and_mannose_metabolism Hs_Function of SLRP in Bone: An Integrated View Hs_FXR and LXR Regulation of Cholesterol Metabolism Hs_G-Protein Signaling Through Tubby Proteins Hs_g-Secretase mediated ErbB4 Signaling Pathway Hs_G13_Signaling_Pathway Hs_Galactose_metabolism Hs_Gamma-aminobutyric Acid Receptor Life Cycle Hs_Gap_Junction_Proteins_Connexins Hs_GATA3 participate in activating the Th2 cytokine genes expression Hs_Generation of amyloid b-peptide by PS1 Hs_Ghrelin: Regulation of Food Intake and Energy Homeostasis Hs_Glucocorticoid_Mineralocorticoid_Metabolism Hs_Glutamate_metabolism Hs_Glutathione_metabolism Hs_Glycine,_serine_and_threonine_metabolism Hs_Glycogen_Metabolism Hs_Glycolysis Pathway Hs_Glycolysis_and_Gluconeogenesis Hs_Glycolysis__Gluconeogenesis Hs_Glyoxylate_and_dicarboxylate_metabolism Hs_GPCRs_Class_A_Rhodopsin-like Hs_GPCRs_Class_B_Secretin_like Hs_GPCRs_Class_C_Metabotropic_glutamate_pheromone Hs_GPCRs_Other Hs_Granzyme A mediated Apoptosis Pathway Hs_Growth Hormone Signaling Pathway Hs_G_Protein_Signaling Hs_Heme_Biosynthesis Hs_Hemoglobins Chaperone Hs_Histidine_metabolism Hs_HIV Induced T Cell Apoptosis Hs_HIV-1 defeats host-mediated resistance by CEM15 Hs_HIV-I Nef: negative effector of Fas and TNF Hs_Hop Pathway in Cardiac Development Hs_How does salmonella hijack a cell Hs_How Progesterone Initiates the Oocyte Maturation Hs_Human Cytomegalovirus and Map Kinase Pathways Hs_Hypoxia and p53 in the Cardiovascular system Hs_Hypoxia-Inducible Factor in the Cardiovascular System Hs_IFN alpha signaling pathway Hs_IFN gamma signaling pathway Hs_IGF-1 Signaling Pathway Hs_IL 17 Signaling Pathway Hs_IL 18 Signaling Pathway Hs_IL 2 signaling pathway Hs_IL 3 signaling pathway Hs_IL 4 signaling pathway Hs_IL 5 Signaling Pathway Hs_IL 6 signaling pathway Hs_IL-10 Anti-inflammatory Signaling Pathway Hs_IL-2 Receptor Beta Chain in T cell Activation Hs_IL-7 Signal Transduction Hs_IL12 and Stat4 Dependent Signaling Pathway in Th1 Development Hs_IL22 Soluble Receptor Signaling Pathway Hs_Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages Hs_Induction of apoptosis through DR3 and DR4/5 Death Receptors Hs_Inflammatory_Response_Pathway Hs_Influence of Ras and Rho proteins on G1 to S Transition Hs_Inhibition of Cellular Proliferation by Gleevec Hs_Inhibition of Huntingtons disease neurodegeneration by histone deacetylase inhibitors Hs_Inhibition of Matrix Metalloproteinases Hs_Inositol_phosphate_metabolism Hs_Insulin Signaling Pathway Hs_Integrin Signaling Pathway Hs_Internal Ribosome entry pathway Hs_Intrinsic Prothrombin Activation Pathway Hs_Ion Channel and Phorbal Esters Signaling Pathway Hs_Ion Channels and Their Functional Role in Vascular Endothelium Hs_Keratinocyte Differentiation Hs_Krebs-TCA_Cycle Hs_Lactose Synthesis Hs_Lck and Fyn tyrosine kinases in initiation of TCR Activation Hs_Lectin Induced Complement Pathway Hs_Leloir pathway of galactose metabolism Hs_Links between Pyk2 and Map Kinases Hs_Lipopolysaccharide_biosynthesis Hs_Lissencephaly gene (LIS1) in neuronal migration and development Hs_Low-density lipoprotein (LDL) pathway during atherogenesis Hs_Lysine_biosynthesis Hs_Lysine_degradation Hs_Malate-aspartate shuttle Hs_Map Kinase Inactivation of SMRT Corepressor Hs_MAPKinase Signaling Pathway Hs_MAPK_Cascade Hs_Matrix_Metalloproteinases Hs_mCalpain and friends in Cell motility Hs_Mechanism of Acetaminophen Activity and Toxicity Hs_Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) Hs_Mechanism of Protein Import into the Nucleus Hs_Mechanisms of transcriptionalrepression by DNA methylation Hs_Melanocyte Development and Pigmentation Pathway Hs_Metabolism of Anandamide, an Endogenous Cannabinoid Hs_Methane_metabolism Hs_Methionine_metabolism Hs_METS affect on Macrophage Differentiation Hs_Mitochondrial Carnitine Palmitoyltransferase (CPT) System Hs_Monoamine_GPCRs Hs_Monocyte and its Surface Molecules Hs_Msp/Ron Receptor Signaling Pathway Hs_mTOR Signaling Pathway Hs_Multi-Drug Resistance Factors Hs_Multi-step Regulation of Transcription by Pitx2 Hs_Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation Hs_Nerve growth factor pathway (NGF) Hs_Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells Hs_Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling Hs_Neutrophil and Its Surface Molecules Hs_NF-kB Signaling Pathway Hs_NFAT and Hypertrophy of the heart (Transcription in the broken heart) Hs_NFkB activation by Nontypeable Hemophilus influenzae Hs_Nicotinate_and_nicotinamide_metabolism Hs_Nitric Oxide Signaling Pathway Hs_Nitrogen-depedent regulation of Rtg1 and Rtg3 in TOR pathway Hs_Nitrogen_metabolism Hs_NO2-dependent IL 12 Pathway in NK cells Hs_Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to fa Hs_Nuclear Receptors in Lipid Metabolism and Toxicity Hs_Nuclear_Receptors Hs_Nucleotide_GPCRs Hs_Nucleotide_Metabolism Hs_Nucleotide_sugars_metabolism Hs_Omega Oxidation Hs_One_carbon_pool_by_folate Hs_Opposing roles of AIF in Apoptosis and Cell Survival Hs_Orphan_GPCRs Hs_Ovarian_Infertility_Genes Hs_Overview of telomerase protein component gene hTert Transcriptional Regulation Hs_Overview of telomerase RNA component gene hTerc Transcriptional Regulation Hs_OX40 Signaling Pathway Hs_Oxidation of odd-numbered chain fatty acid, from Propionyl-CoA to Succinyl-CoA Hs_Oxidative reactions of the pentose phosphate pathway Hs_Oxidative Stress Induced Gene Expression Via Nrf2 Hs_Oxidative_phosphorylation Hs_p38 MAPK Signaling Pathway Hs_p53 Signaling Pathway Hs_Pantothenate_and_CoA_biosynthesis Hs_PDGF Signaling Pathway Hs_Pelp1 Modulation of Estrogen Receptor Activity Hs_Pentose_and_glucuronate_interconversions Hs_Pentose_Phosphate_Pathway Hs_Peptide_GPCRs Hs_Pertussis toxin-insensitive CCR5 Signaling in Macrophage Hs_Phenylalanine,_tyrosine_and_tryptophan_biosynthesis Hs_Phenylalanine_metabolism Hs_Phosphatidylcholine Biosynthesis Pathway Hs_Phosphoinositides and their downstream targets Hs_Phospholipase C d1 in phospholipid associated cell signaling Hs_Phospholipase C Signaling Pathway Hs_Phospholipase C-epsilon pathway Hs_Phospholipid Biosynthesis in E. Coli Pathway Hs_Phospholipids as signalling intermediaries Hs_Phospholipid_degradation Hs_Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway Hs_PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase Hs_Platelet Amyloid Precursor Protein Pathway Hs_Polyadenylation of mRNA Hs_Porphyrin_and_chlorophyll_metabolism Hs_Presenilin action in Notch and Wnt signaling Hs_Prion Pathway Hs_Proepithelin Conversion to Epithelin and Wound Repair Control Hs_Propanoate_metabolism Hs_Prostaglandin_and_leukotriene_metabolism Hs_Proteasome Complex Hs_Proteasome_Degradation Hs_Protein Kinase A at the Centrosome Hs_Proteolysis and Signaling Pathway of Notch Hs_PTEN dependent cell cycle arrest and apoptosis Hs_Purine_metabolism Hs_Pyrimidine_metabolism Hs_Pyruvate_metabolism Hs_Rab GTPases Mark Targets In The Endocytotic Machinery Hs_Rac 1 cell motility signaling pathway Hs_Ras Signaling Pathway Hs_Ras-Independent pathway in NK cell-mediated cytotoxicity Hs_RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage Hs_Reductive_carboxylate_cycle_(CO2_fixation) Hs_Reelin Signaling Pathway Hs_Regulation of BAD phosphorylation Hs_Regulation of cell cycle progression by Plk3 Hs_Regulation of ck1/cdk5 by type 1 glutamate receptors Hs_Regulation of eIF2 Hs_Regulation of eIF4e and p70 S6 Kinase Hs_Regulation of hematopoiesis by cytokines Hs_Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases Hs_Regulation of p27 Phosphorylation during Cell Cycle Progression Hs_Regulation of PGC-1a Hs_Regulation of Spermatogenesis by CREM Hs_Regulation of Splicing through Sam68 Hs_Regulation of transcriptional activity by PML Hs_Regulators of Bone Mineralization Hs_Repression of Pain Sensation by the Transcriptional Regulator DREAM Hs_Reversal of Insulin Resistance by Leptin Hs_Rgt1 in Yeast Glucose Induction Pathway Hs_Rho cell motility signaling pathway Hs_Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation Hs_Riboflavin_metabolism Hs_Ribosomal_Proteins Hs_RNA polymerase III transcription Hs_Role of ?arrestins in the activation and targeting of MAP kinases Hs_Role of BRCA1,BRCA2 and ATR in Cancer Susceptibility Hs_Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy Hs_Role of ERBB2 in Signal Transduction and Oncology Hs_Role of Erk5 in Neuronal Survival Hs_Role of MAL in Rho-Mediated Activation of SRF Hs_Role of MEF2D in T-cell Apoptosis Hs_Role of Mitochondria in Apoptotic Signaling Hs_Role of nicotinic acetylcholine receptors in the regulation of apoptosis Hs_Role of Parkin in the Ubiquitin-Proteasomal Pathway Hs_Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration Hs_Role of PPAR-gamma Coactivators in Obesity and Thermogenesis Hs_Role of Ran in mitotic spindle regulation Hs_Role of Tob in T-cell activation Hs_Roles of ?arrestin-dependent Recruitment of Src Kinases in GPCR Signaling Hs_S1P_Signaling Hs_SARS Coronavirus Protease Hs_Segmentation Clock Hs_Selective expression of chemokine receptors during T-cell polarization Hs_Selenoamino_acid_metabolism Hs_Shuttle for transfer of acetyl groups from mitochondria to the cytosol Hs_Signal Dependent Regulation of Myogenesis by Corepressor MITR Hs_Signal transduction through IL1R Hs_Signaling of Hepatocyte Growth Factor Receptor Hs_Signaling Pathway from G-Protein Families Hs_Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway Hs_Small Leucine-rich Proteoglycan (SLRP) molecules Hs_Smal_ligand_GPCRs Hs_Snf1 in Yeast Glucose Repression/Derepression Hs_SODD/TNFR1 Signaling Pathway Hs_Sonic Hedgehog (Shh) Pathway Hs_Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle Hs_Sphingoglycolipid_metabolism Hs_Sphingophospholipid_biosynthesis Hs_Spliceosomal Assembly Hs_Sprouty regulation of tyrosine kinase signals Hs_SREBP control of lipid synthesis Hs_Stat3 Signaling Pathway Hs_Stathmin and breast cancer resistance to antimicrotubule agents Hs_Steps in the Glycosylation of Mammalian N-linked Oligosaccarides Hs_Steroid_Biosynthesis Hs_Stress Induction ofHsP Regulation Hs_Sulfur_metabolism Hs_SUMOylation as a mechanism to modulate CtBP-dependent gene responses Hs_Sumoylation by RanBP2 Regulates Transcriptional Repression Hs_Synaptic Proteins at the Synaptic Junction Hs_Synthesis_and_degradation_of_ketone_bodies Hs_T Cell Receptor and CD3 Complex Hs_T Cell Receptor Signaling Pathway Hs_T Cytotoxic Cell Surface Molecules Hs_T Helper Cell Surface Molecules Hs_TACI and BCMA stimulation of B cell immune responses Hs_Taurine_and_hypotaurine_metabolism Hs_Telomeres, Telomerase, Cellular Aging, andImmortality Hs_Terpenoid_biosynthesis Hs_TGF beta signaling pathway Hs_TGF_Beta_Signaling_Pathway Hs_Th1/Th2 Differentiation Hs_The 4-1BB-dependent immune response Hs_The Citric Acid Cycle Hs_The Co-Stimulatory Signal During T-cell Activation Hs_The IGF-1 Receptor and Longevity Hs_The information-processing pathway at the IFN-beta enhancer Hs_The PRC2 Complex sets Long-term gene Silencing The Modification of Histone Tails Hs_The reactions that feed amino groups into the urea cycle Hs_The Role of Eosinophils in the Chemokine Network of Allergy Hs_The role of FYVE-finger proteins in vesicle transport Hs_The salvage pathway from serine to phosphatidylcholine Hs_Thrombin signaling and protease-activated receptors Hs_TNF/Stress Related Signaling Hs_TNFR1 Signaling Pathway Hs_TNFR2 Signaling Pathway Hs_Toll-Like Receptor Pathway Hs_TPO Signaling Pathway Hs_Transcription factor CREB and its extracellular signals Hs_Transcription Regulation by Methyltransferase of CARM1 Hs_Transcriptional activation of dbpb from mRNA Hs_Translation_Factors Hs_Trefoil Factors InitiateMucosal Healing Hs_Trka Receptor Signaling Pathway Hs_tRNA_Synthetases Hs_Tryptophan_metabolism Hs_TSP-1 Induced Apoptosis in Microvascular Endothelial Cell Hs_Tumor Suppressor Arf Inhibits Ribosomal Biogenesis Hs_Tyrosine_metabolism Hs_Ubiquinone_biosynthesis Hs_uCalpain and friends in Cell spread Hs_Urea_cycle_and_metabolism_of_amino_groups Hs_Valine,_leucine_and_isoleucine_degradation Hs_VEGF, Hypoxia, and Angiogenesis Hs_Visceral Fat Deposits and the Metabolic Syndrome Hs_Visual Signal Transduction Hs_Vitamin C in the Brain Hs_West Nile Virus Hs_WNT Signaling Pathway Hs_Wnt/LRP6 Signalling Hs_Wnt_signaling Hs_Y branching of actin filaments
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